Prosight Management, L.P. 13F annual report

Prosight Management, L.P. is an investment fund managing more than $335 billion ran by Ryan Cappelli. There are currently 46 companies in Mr. Cappelli’s portfolio. The largest investments include Galapagos NV and ADC Therapeutics SA, together worth $63.7 billion.

Limited to 30 biggest holdings

$335 billion Assets Under Management (AUM)

As of 7th August 2024, Prosight Management, L.P.’s top holding is 1,349,980 shares of Galapagos NV currently worth over $33.5 billion and making up 10.0% of the portfolio value. Relative to the number of outstanding shares of Galapagos NV, Prosight Management, L.P. owns more than approximately 0.1% of the company. In addition, the fund holds 9,570,000 shares of ADC Therapeutics SA worth $30.2 billion, whose value fell 42.2% in the past six months. The third-largest holding is Roivant Sciences Ltd worth $21.1 billion and the next is BridgeBio Pharma Inc worth $20.3 billion, with 800,000 shares owned.

Currently, Prosight Management, L.P.'s portfolio is worth at least $335 billion. The total portfolio value may be much higher due to cash assets that are not publicly disclosed such as fixed income, real estate, or cash equivalents.

Careers at Prosight Management, L.P.

The Prosight Management, L.P. office and employees reside in Dallas, Texas. According to the last 13-F report filed with the SEC, Ryan Cappelli serves as the Chief Compliance Officer/Chief Operating Officer at Prosight Management, L.P..

Recent trades

In the most recent 13F filing, Prosight Management, L.P. revealed that it had opened a new position in Roivant Sciences Ltd and bought 2,000,000 shares worth $21.1 billion.

The investment fund also strengthened its position in Galapagos NV by buying 522,686 additional shares. This makes their stake in Galapagos NV total 1,349,980 shares worth $33.5 billion. Galapagos NV dropped 37.7% in the past year.

On the other hand, there are companies that Prosight Management, L.P. is getting rid of from its portfolio. Prosight Management, L.P. closed its position in Oric Pharmaceuticals on 14th August 2024. It sold the previously owned 1,578,263 shares for $14.5 billion. Ryan Cappelli also disclosed a decreased stake in Kura Oncology Inc by 0.3%. This leaves the value of the investment at $13 billion and 629,900 shares.

One of the smaller hedge funds

The two most similar investment funds to Prosight Management, L.P. are Sws Partners and El Puerto De Liverpool, S.a.b. De C.v. They manage $335 billion and $334 billion respectively.


Ryan Cappelli investment strategy

Prosight Management, L.P.’s portfolio is diversified across 2 sectors. Currently, their heaviest sector is Health Care — making up 74.7% of the total portfolio value. The fund focuses on investments in the United States as 56.5% of the portfolio companies are based in the United States.

The majority of the companies in the fund’s portfolio are large-cap stocks. Stocks with a size of more than $10 billion in market cap make up 11% of the total holdings value. On the other hand, small-cap stocks make up only 4.3% of the portfolio. The average market cap of the portfolio companies is close to $10.5 billion.

The complete list of Prosight Management, L.P. trades based on 13F SEC filings

These positions were updated on August 14th based on the fund’s latest 13F filing. Quickly find out what the most recently closed or increased positions are.

Security Shares Owned Value Allocation
Galapagos NV
63.18%
1,349,980
$33,452,504,000 10.00%
ADC Therapeutics SA
47.87%
9,570,000
$30,241,200,000 9.04%
Roivant Sciences Ltd
Opened
2,000,000
$21,140,000,000 6.32%
BridgeBio Pharma Inc
Opened
800,000
$20,264,000,000 6.06%
Zimmer Biomet Holdings Inc
Opened
170,000
$18,450,100,000 5.51%
Meiragtx Hldgs Plc
7.46%
4,352,700
$18,324,867,000 5.48%
Shattuck Labs, Inc.
67.82%
4,670,000
$18,026,200,000 5.39%
Oric Pharmaceuticals, Inc.
Closed
1,578,263
$14,520,020,000
Kura Oncology Inc
33.69%
629,900
$12,969,641,000 3.88%
Cytokinetics Inc
Opened
230,000
$12,461,400,000 3.72%
Syndax Pharmaceuticals Inc
Opened
551,544
$11,323,198,000 3.38%
Mirum Pharmaceuticals Inc
7.33%
314,800
$10,763,012,000 3.22%
Kelly Svcs Inc
Opened
492,340
$10,540,999,000 3.15%
Zymeworks Inc
Opened
1,180,000
$10,041,800,000 3.00%
QuidelOrtho Corporation
Closed
118,920
$8,764,404,000
Pacira BioSciences Inc
Closed
258,424
$8,719,226,000
Immunovant Inc
Opened
325,000
$8,580,000,000 2.56%
Schrodinger, Inc.
Opened
369,261
$7,141,508,000 2.13%
AbCellera Biologics Inc.
38.39%
2,352,633
$6,963,794,000 2.08%
Alkermes plc
1,733.33%
275,000
$6,627,500,000 1.98%
Erasca Inc
358.75%
2,750,000
$6,490,000,000 1.94%
Viking Therapeutics Inc
Opened
115,000
$6,096,150,000 1.82%
Prothena Corp Plc
25.00%
286,926
$5,922,153,000 1.77%
OrthoPediatrics corp
110.75%
200,216
$5,758,212,000 1.72%
Option Care Health, Inc.
37.77%
205,000
$5,678,500,000 1.70%
Dexcom Inc
114.42%
49,317
$5,591,561,000 1.67%
Accolade, Inc.
Opened
1,489,525
$5,332,500,000 1.59%
Cogent Biosciences, Inc.
Opened
500,000
$4,215,000,000 1.26%
Neurocrine Biosciences, Inc.
24.79%
27,000
$3,717,090,000 1.11%
Graphite Bio
Closed
1,351,939
$3,542,080,000
Nuvation Bio Cl A
Closed
2,050,000
$3,095,500,000
Relay Therapeutics, Inc.
Opened
385,000
$2,510,200,000 0.75%
Biocryst Pharmaceuticals Inc.
82.14%
398,700
$2,463,966,000 0.74%
CVS Health Corp
Opened
40,000
$2,362,400,000 0.71%
Medtronic Plc
86.36%
30,000
$2,361,300,000 0.71%
Vincerx Pharma Inc
Opened
2,488,418
$2,015,619,000 0.60%
Veradigm Inc
Closed
180,000
$1,888,200,000
Inspire Med Sys Inc
Opened
14,000
$1,873,620,000 0.56%
Paragon 28, Inc.
Opened
261,400
$1,787,976,000 0.53%
Universal Hlth Svcs Inc
66.63%
9,373
$1,733,349,000 0.52%
Privia Health Group Inc
27.31%
96,065
$1,669,610,000 0.50%
Barrett Business Services Inc.
Closed
13,000
$1,505,400,000
Mural Oncology Pub Ltd Co
13.61%
475,458
$1,492,938,000 0.45%
Addus HomeCare Corporation
Opened
12,500
$1,451,375,000 0.43%
Spyre Therapeutics
Closed
55,000
$1,183,600,000
Tectonic Therapeutic Inc
Opened
67,461
$1,111,083,000 0.33%
Lenz Therapeutics Inc
Opened
59,542
$1,029,481,000 0.31%
10x Genomics, Inc.
Opened
49,021
$953,458,000 0.28%
Shockwave Medical Inc.
Closed
5,000
$952,800,000
Ovid Therapeutics Inc
Opened
1,075,000
$826,890,000 0.25%
Immunome, Inc.
Opened
65,000
$786,500,000 0.24%
Design Therapeutics
Closed
280,000
$742,000,000
Aileron Therapeutics Inc
Opened
265,000
$734,050,000 0.22%
Immuneering Corp
Opened
550,000
$704,000,000 0.21%
Biomea Fusion Inc
189.31%
124,377
$559,697,000 0.17%
Kezar Life Sciences Inc
98.33%
56,080
$33,648,000 0.01%
No transactions found
Showing first 500 out of 56 holdings